RU58841 is a non-steroidal experimental anti-androgen, which is intended for use as a topical treatment for acne and androgenic alopecia (male pattern baldness).
To briefly describe how it works, it is basically a turn-key all in one hair loss compound that blocks all DHT on the scalp, and can significantly improve the life of anybody experiencing hair loss, and I’m shocked it isn’t more heavily researched.
I will be “researching” RU for the rest of my life unless something better gets invented.
For beginners who have never researched RU58841, I always recommend getting 3 pre-mixed RU58841 solutions with 5% strength to start off.
This should last you around 5-6 months, and is a perfect time frame to assess how you respond to RU58841, and if you would like to continue your research past that point.
For the carrier (what the RU58841 raw powder is mixed in), I prefer PG (propylene glycol) + Ethanol.
I find it rare for someone’s scalp to be irritated by the PG/Ethanol to the point of needing K&B instead as the carrier. They both work fine; some people just seem to have skin irritation to particular carriers as opposed to others.
Keep in mind, in the short-term, it is actually cheaper to buy your solutions pre-mixed already for you. It is only once you have decided that you will be using RU58841 long-term that it becomes more cost effective to invest in the raw powders, and getting the other necessary tools/ingredients to make your own solutions at home.
If You Have A Very Hard Time Finding Ethanol
If you want to reconstitute your own solutions and can’t find Ethanol by itself (it’s not easy to find) then Anagen’s K&B solution is your best alternative.
It comes in a pre-mixed 50ml bottle mixed with Ethanol, Deionized Water/Demineralized Water, and K&B emulsifiers.
It actually makes research really convenient as if you use the K&B solution you can completely skip over this article, which will outline the process of how to make the RU58841 solution in the typical Ethanol and Propylene Glycol vehicle.
All that is required with the K&B solution is to pour your desired amount of RU58841 powder into the premixed K&B solution, then shake lightly until it is thoroughly dissolved and mixed evenly.
If you want to mix the standard concentration, use 2.5 grams of raw RU58841 powder in a 50ml K&B solution to achieve a 5% RU58841 solution of 50mg/ml.
What You Will Need To Mix Your Own RU58841 Solutions/The Cheapest Long-Term Method
First thing you want to do is grab a 50ml measuring beaker and fill it up with 35ml of Ethanol.
After you’ve done that, turn on your scale and make sure it’s measuring in grams as its’ unit of measurement.
Once you see that it’s turned on and at 0 grams, put your other beaker (the empty one) on the scale.
After the measurement has stabilized, turn the scale back to 0 with the beaker still on it by pressing the “Tare” button.
Once you press this, it will reset the scale to 0 even with the beaker on it. The purpose of this is so we can determine what 2.5 grams of RU5881 powder is without the beaker screwing up our measurement.
Add 2.5 grams of powder to the empty beaker on the scale until you see the scale reading 2.5 grams.
Once you’ve done that, you can turn off the scale and put it away.
Next, pour the 35ml of Ethanol from one beaker into the beaker with the 2.5 grams of RU58841 raw powder.
Right after, take that empty beaker you just emptied the Ethanol out of and fill it up with 15ml of Propylene Glycol.
The ideal vehicle proportion for an Ethanol and Propylene Glycol RU58841 solution is 70% Ethanol/30% Propylene Glycol (I find it works the best).
So no matter how much solution you are using, even if you made a 100 ml solution, you would still want 70% of it to be Ethanol and the other 30% to be Propylene Glycol.
For our solution we’re mixing now, it is 50ml so we want 70% (35ml) as Ethanol, and 30% (15ml) as Propylene Glycol.
So once you’ve filled up 15ml of Propylene Glycol, pour that into the beaker that has your Ethanol and RU58841 in it.
You should now have a cloudy solution of RU58841.
All you need to do now is get your glass stirring rod, and stir the solution until it is crystal clear and you can’t see any fragments of unmixed RU58841 powder in it.
If you are stirring for a while and can’t seem to get it to completely mix, simply add a few more millilitres of Ethanol and Propylene Glycol to the solution to dilute it a bit more (remembering to use 70% of what you’re adding as Ethanol, and 30% of what you’re adding as Propylene Glycol).
Once it’s crystal clear your solution is ready to go, and you can get your funnel and 50ml+ RU58841 container and pour the solution through the funnel into the empty bottle you have to store your solution in.
There you have it, now you have a 50ml+ 5% RU58841 solution dosed at 50mg/ml.
Store it in the freezer out of the light ideally to maximize the shelf life and prevent any degradation to the solution.
You can store it in the fridge as well as long as it’s out of light.
Room temperature is the least ideal scenario, but if you don’t have a fridge or freezer you can store it in, then at least make sure it’s in a cool, dry place, out of direct light when you’re storing it at room temperature.
Just for your reference though, a RU58841 solution can remain stable without degrading stored in the freezer the longest, with the fridge being second, and then room temperature degrading significantly faster than the two other far more ideal storage locations.
This article is intended for educational/informational purposes only. This product is intended as a research chemical only.