LGD-4033 Vs Ostarine Article Thumbnail

LGD-4033 Vs Ostarine – Which SARM Is Better And Why?

LGD-4033 Vs Ostarine

LGD-4033 vs Ostarine is the most common comparison you will see between SARMs.

Both Ligandrol (LGD-4033) and MK-2866 (Ostarine) have gained a lot of popularity over the last half decade in the bodybuilding community as fantastic muscle building agents.

The question on everybody’s mind is, which is better?

I’m going to break it down for you, as it isn’t as cut and dry as one is outright better than the other.

Size And Strength Gains/Bulking

LGD-4033 has an unmatched ability to build muscle mass relative to other SARMs.

Milligram for milligram, it even outperforms many of the most potent anabolic androgenic steroids.

LGD-4033 Vs Ostarine Increase In Muscle Mass
LGD-4033 Vs Ostarine (VK5211 Vs Enobosarm) Vs Nandrolone (Deca)

While some SARMs come close like S23, LGD-4033 shines in its ability to pack on size and strength.

Ostarine is effective as well, but LGD-4033 is the tip of the iceberg when it comes to gains in muscle mass per milligram as of now.

LGD-4033 is reported to be “watery” by several individuals.

By that, they mean it has a propensity to cause some water retention.

I have never seen that myself personally, and I believe it is more likely a diet and body composition issue being compounded by Ligandrol's mechanism of action in the body in some capacity, rather than the SARM inherently bloating people up.

For example, a completely garbage diet on Anadrol will bloat you like crazy, but if your diet is in check, you're lean, and you're not overeating, you will not bloat whatsoever.

Anadrol is commonly used by bodybuilders pre-contest all the way up to the day of their competition because it simply will not bloat you if you're in shape.

Instead, it will just help you hold intramuscular fullness and maintain a severely elevated red blood cell count (extremely unhealthy, but helpful for the stage nonetheless).

With that being said, if water retention is exacerbated by diet choices in a calorie surplus, then it may artificially inflate the perceived benefits of LGD-4033, sort of like Dianabol.

Based on personal experience, I can say that it is still superior to Ostarine at building muscle, even when factoring this possibility in, and there is a significant amount of clinical data to back this up as well.

When it comes to strength gains, the difference between Ostarine and LGD-4033 is not as staggering as the difference between their gains in muscle size, however, LGD-4033 still edges it out in that category as well.

For Cutting

Muscle preservation is the goal while cutting, not building muscle and strength.

The anabolic demands of a cut phase are lower during a phase of muscle preservation than during a phase of trying to gain supraphyisological amounts of muscle tissue.

The only purpose “cutting” compounds truly serve is to create a certain cosmetic look on stage.

Muscle preservation can be accomplished fairly easily with an array of different compounds with equivalent levels of success, the only thing that makes one cut phase yield different body composition outcomes than another are the androgens used in the weeks leading up to the competition that can dry out the muscle, or provide a granite look that otherwise wouldn't have been achievable at that same body fat percentage.

This is less relevant to our comparison of LGD-4033 vs Ostarine, but it's a good way to exemplify how at the end of the day both will prove sufficient anabolic aids for retaining muscle tissue and strength in a calorie deficit.

One reason that Ostarine is often preferred during a cutting phase is the perceived lack of water retention relative to LGD-4033.

Again, neither compound will bloat a lean physique in a strict deficit with a clean diet.

However, some users report a dryer, harder look from Ostarine.

In addition, calorie restriction and getting extremely lean will inevitably lower natural Testosterone levels.

It's an unavoidable outcome that natural bodybuilders have to endure.

While SARMs will help prevent catabolism during this calorie restricted phase of suppressed Testosterone production, the SARMs further exacerbate Testosterone suppression by suppressing luteinizing hormone (LH) and follicle stimulating hormone (FSH) through the hypothalamus-pituitary-testis axis [R].


This is where Ostarine can arguably edge out LGD-4033, as it is significantly less suppressive.

While muscle loss could be staved off with the use of either SARM, the likelihood of low-Testosterone related sexual dysfunction and other androgen deficiency related side effects are less likely to occur with Ostarine.

Both SARMs exhibit blatant endocrine suppression in a dose-dependent manner, LGD-4033 milligram to milligram is far more suppressive than Ostarine though, and low-Testosterone related side effects are reported more often from Ligandrol users.

Consequently, it is absolutely IMPERATIVE that you complete a PCT (post-cycle therapy) after your Ostarine, LGD-4033, or SARMs cycle in general finishes.

This means literally the day after your last Ostarine or LGD-4033 dose, you begin your PCT.

If you don’t screw this up, you will likely encounter no issues and should recover in a very timely manner.

I don't endorse the use of either compound, but if you're going to be using them anyways you should be aware of their very real side effects.

Do not use performance enhancing compounds at all if you haven't done sufficient research prior to starting them with a complete concrete game plan of how you are going to address and mitigate potential health implications should they arise.

Both SARMs will cause some degree of Testosterone suppression at the dosages commonly used for bodybuilding purposes.

In Conclusion

Ostarine and LGD-4033 both have their place and serve a very useful purpose.

By researching and understanding how they work in contrast to one another, their potential side effects and their efficacy profiles, you can make a more informed decision about what you feel is ideal for your individual specific goals.

These Are My Current Trusted/Go To Companies For Third Party Tested SARMs:

Chemyo – 10% off coupon code “DC10”

Amino Asylum – 20% off coupon code “DC20”

Swiss Chems – 10% off coupon code “DC10”

Disclaimer: The information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws.


Get My "20 Underground Bodybuilding Secrets You Won't Find On Google" E-Book 100% FREE

More Plates More Dates Free eBook with 20 bodybuilding secrets

Also Get Updated Every Time I Publish New Content And Receive FREE Exclusive Offers

We won't share your information with anyone.

About Derek

After dedicating over 8 years to extreme self-improvement, I have created "More Plates More Dates" as a one stop shop for helping you to get yourself on the right path to the "best you" possible too.


Subscribe For Free E-Book

Subscribe and get my “20 Underground Bodybuilding Secrets You Won’t Find On Google” E-Book 100% FREE

Subscribe For Free E-Book

Subscribe and get my “20 Underground Bodybuilding Secrets You Won’t Find On Google” E-Book 100% FREE

Subscribe For Free E-Book

Subscribe and get my “20 Underground Bodybuilding Secrets You Won’t Find On Google” E-Book 100% FREE