Your First SARMs Cycle Thumbnail

First SARMs Cycle – Key Fundamental Concepts & Basic Do’s & Don’ts

This will be a very general overview of some basic do’s and don’ts that you should strongly take into consideration prior to embarking on your first SARMs cycle.

For those that are just here find out where to buy accurately dosed, third party tested SARMs, these are the only companies I currently use for my own personal research:

(Greater Than 99% Purity: FTIR, HPLC, GC-MS, LC-MS & NMR Tested)

Science.bio – 10% off coupon code “DC10”

Chemyo – 10% off coupon code “DC10”

Amino Asylum – 20% off coupon code “DC20”

Swiss Chems – 25% off coupon code “DC25”

Use Only One Suppressive SARM On Your First Cycle

This strategy should be employed so you can properly mitigate side effects or issues should you encounter them.

If you embark on your first SARMs cycle with a boat load of different compounds and you experience a major side effect you may not be able to discern which compound it is that is causing your issues, and not be able to mitigate that side effect effectively.

Even a cycle of two compounds is too much for your first SARMs cycle.

If you have zero experience with SARMs and then you incorporate LGD-4033 and Ostarine at the same time and experience an unexpected side effect, you will likely have a difficult time trying to figure out what's going on, which compound is causing the side effect, or if it's a combination of the two.

By sticking to one suppressive compound during your first SARMs cycle you can effectively limit the potential occurrence of side effects, as well as simplify the process of deducing what is causing your side effects should you encounter any unforeseen complications.

If you have no idea how your body will react to one compound, it would be a terrible idea to throw several into your body at once.

Understand How The SARM Works BEFORE Using It

Understand what the SARM you want to use does, its possible side effects, its effective dose, etc. before you start using it.

There are far too many guys who will just hear a random gym bro say “yo use this one, it’s the best” and then hop on a cycle of it without even knowing the rudimentary information about the compound that is necessary to understand.

If you don’t know what you’re putting in your own body you will have no idea what to expect, how to properly utilize it, how to mitigate side effects, how to make adjustments when necessary, among countless other factors.

Research the compound thoroughly prior to starting any cycle.

Understand What Post-Cycle Therapy Is (PCT), Why It Is Crucial, And How To Properly Go About It

PCT is an absolute necessity.

Regardless of what you’ve been told, if you are using something that will suppress your endocrine system it would be wise to complete a PCT phase in some capacity.

While some individuals could likely get away with no PCT at all and recover just fine, this is absolutely not the case for some others, and it would be far safer for everyone to just do a proper PCT regimen after any cycle.

For mild single compound cycles like Ostarine, a simple 4 week PCT of 75mg Arimistane per day is typically sufficient.

However, this does not mean this is always the best choice, as this may not suffice for some individuals.

In the event that one experiences substantial testosterone suppression as a result of running a longer, higher dosed, or multiple SARM compound cycle, or they just have a higher propensity to suppression than the average guy, it is likely that deploying a PCT comprised of Nolvadex (Tamoxifen Citrate) and Clomid (Clomiphene Citrate) will be necessary instead.

A standard Nolvadex and Clomid PCT for a SARMs cycle typically breaks down as follows:

Week 1-4 (the four weeks immediately following the last SARM dose):

Week 1: Nolvadex – 40mg per day, Clomid – 50mg per day

Week 2: Nolvadex – 40mg per day, Clomid – 50mg per day

Week 3: Nolvadex – 20mg per day, Clomid – 25mg per day

Week 4: Nolvadex – 20mg per day, Clomid – 25mg per day

Continue To Diet And Train As Hard As You Were On Cycle Once You Go Off Cycle

If you train hard and eat properly on cycle and get fantastic gains, it doesn’t mean that you can let off the gas simply because you are now “off cycle.”

One of the main factors that will dictate how much muscle you retain from your first SARM cycle will be if you continue to train hard and eat well even once you come off cycle.

For some reason, many individuals think that because they have no anabolic assistance that they might as well throw their diet out the window and start taking it easy with their training.

This couldn’t be further from the truth, and doing this will just cause the hard earned muscle you just built to melt off your body.

You need to continue to train as hard and eat as well as you were on cycle, even when you are off cycle if you want to retain all of your gains from that cycle.

You are already going to be fighting an uphill battle with a suppressed endocrine system that is recovering, so your training and diet needs to be 100% on point.

Plan Your Cycle Time Frame Appropriately For Your Goals

One thing that needs to be understood about muscle building is it is a slow process.

You cannot build an appreciable amount of muscle in 4 weeks, so even if you are on boatloads of anabolic assistance, doing a 4 week cycle in hopes of gaining a substantial amount of muscle is wishful thinking.

A productive bulk (in my opinion) should be around 12 weeks, and should be longer for some.

But for the sake of this article being for newbies doing their first SARMs cycle, 8-12 weeks would be more than sufficient to notice a substantial amount of progress.

After 2-3 months your gains will likely start to plateau as Myostatin levels increase, and that is when cycling off to recover endocrine function and reset Myostatin would be appropriate.

Doing mini-blasts of Ostarine or LGD-4033 for 3-4 weeks like some guys are doing is almost pointless.

All you are doing is getting some glycogen and nitrogen retention benefits, increased blood volume, and a minor amount of muscle gain.

The compound will have hardly saturated in your system yet, and barely any hypertrophy will occur by the time you are going off cycle.

If you are bulking, your cycle length should be an appropriate amount of time for your body to actually accrue a decent amount of new muscle mass, and to build on your strength levels while you slowly taper up your calorie intake.

The cycle length for cutting on the other hand should be however long it takes you to get to your desired body fat percentage.

The point of SARMs during a cut is to retain the lean muscle you have, so it only makes sense that the duration of your cut cycle should be as long as it takes to burn the amount of fat necessary to reach your desired level of body fat.

For me, that is typically around 8-12 weeks.

Have A Decent Understanding Of Diet And Training First

One of the main issues with a newbie starting their first SARMs cycle after barely having trained naturally isn’t always just that their endocrine system hasn’t fully finished developing yet, but also it is that in almost all cases a newbie will not have a strong grasp of proper diet and training for several years.

Typically, a newbie will start a cycle before even building a proper foundation of muscle on a natural base, and that may limit their long-term potential (this is debatable).

One thing it will definitely result in though is subpar cycle results.

What is the point of subjecting your body to hormonal suppression and other possible side effects if you don’t even know how to diet and train?

There isn’t.

Most guys who don’t experience decent on-cycle results simply have no clue what they are doing at the gym or how to properly diet, and then they wonder why they aren’t getting bigger despite having multiple cycles under their belt.

Diet and training are the fundamentals and are key.

Get a solid understanding of that before you even consider anabolics is my suggestion.

Have An Aromatase Inhibitor (AI) On Hand Just In Case

Estrogen related issues can rear their ugly head on cycle, and if you aren’t prepared with an AI to combat them, you could be stuck dealing with a myriad of undesirable side effects.

For cycles comprised only of SARMs (and not additional Steroids or other aromatizing Prohormones), you shouldn’t have Estrogen related issues substantial enough to warrant using a Rx Aromatase Inhibitor like Aromasin, Arimidex, or Letrozole.

Arimistane should be perfectly sufficient for keeping your Estrogen in the sweet spot during any SARM cycle.

A minority of individuals may need a low dose of Aromasin and that will typically be dictated by body composition, lifestyle, diet and genetics.

I suggest having an AI on hand just in case prior to starting any SARMs cycle.

Be Patient

This is one of the most important things you must do.

Building muscle, and then stripping fat off, and then building muscle, and then stripping fat off, over and over is a very long-term commitment, and results will seem slow to those who are impatient.

Even on cycle everyone wants to gain 15-20+ pounds of muscle, but it just doesn’t work like that for most people.

Building a great physique is a slow process that takes at least a few years (unless you are a genetic freak), and you need to be patient during this building process.

Rome wasn’t built in a day, and neither will your ideal physique.

Where To Buy SARMs

Most SARMs sources do not third party test their products, nor do they have any satisfactory level of quality control whatsoever.

I strongly advise that before you buy SARMs from a company online you thoroughly evaluate their track record, their third party test results, and how they are marketing their products in general.

These Are My Current Trusted/Go To Companies For Third Party Tested 99%+ Pure SARMs:

Disclaimer: The information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws.

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168 thoughts on “First SARMs Cycle – Key Fundamental Concepts & Basic Do’s & Don’ts”

  1. Brian Williams

    I’m starting my first liquid Sarms cycle starting on Monday. I’ve been training at the gym for about 2months and have seen good results already. Question, what’s the most effective way to take lgd 4033 liquid? With water? Pre workout? Please let me know
    Brian Williams

      1. I have a question. I just finished rad-140. I did only 4 weeks of that but before that I was taking a 1,4andro supplement by Spartan nutrition so I was also stacking that with the rad-140 and lgd3303. I finished the 1,4 and go and the raw but still have the lgd3303. I’m almost done with it. Do you recommend that I do Clomid for pct as soon as my lgd finishes? I was gonna run Clomid with mk2866 for pct for 4 weeks. And then after the 4 weeks was gonna do another cycle. What do you think? Should u have continued another 8 weeks with the sarms to make it 12 weeks or should I just jump into my pct as soon as my lgd is finished since I already did rad and the 1,4 android supplement.

        1. Derek hows or going man? I’ve been training naturally for about 3 month now with proper dieting and exercising ofcourse. I’ve definitely gotten good results. Im thinking of taking sarms and wanted to ask you what would be a good beginner sarms with little to no side effect on lower doses. Would taking Mk-678 with LGD4 make sense?

    1. I’m planning on running a 12 week Ostarine and Cardarine cycle at typical doses (25mg for Osta, 20mg for GW). Because my cycle is on the longer side, does that mean I’ll have to use a SERM such as Nolva or Clomid for PCT or would arimistane do the trick still?

      1. Michael Brughelli

        Why do you recommend an AI as PCT for Ostarine? Since sarms don’t aromatise, won’t estradiol be suppressed at the end of a cycle? This makes no sense. And sarms don’t significantly lower LH, so why would you recommend PCT at all? Nolva and clomid have long half lives.. by the time it reaches therapeutic levels in the blood, you’ll likely be halfway recovered naturally. Not to mention the host of side effects serms can cause.

    2. Michael Allen Clifford

      Would you use arimistane during the entire cycle? Or would you just use it when estrogenic side effects appear?

  2. One of the stacks you recommended was 10mg LGD 4033 per morning with 20g MK-677 per evening, with 1 Arim-Rx per day of cycle. Is the Arim-Rx daily while on a 12 week long cycle of the other two enough of a PCT? If not, are there any non-prescription PCTs that you can recommend? (I know you’ve suggested Novaldex and Clomid, but I may not be able to get a doctor’s prescription for those, and believe prescriptions are required for those two.)

    1. Great review, thanks for your experience! I notice that Anabolics, the Canadian company, cherry picks their reviews and of course doesn’t okay anything not flattering. I tried their stuff and gave an honest review claiming it didn’t do a thing for me, and it wasn’t posted. Does this sound like a company that is on the up and up?

  3. Hey man, firstly thanks for all the info you put up on your website, has helped me out a lot recently.
    I’m currently on my second SARM cycle at week 3 of LGD 4033 + MK 677 and loving it! I’m planning to run this cycle for 12 weeks. My question is, could I possibly run another 12 weeks of MK 2866 + RAD 140 straight after LGD 4033 + MK 677? Or should I PCT and wait 4 weeks instead? Thanks again!

    1. You can do whatever you want but your recovery is going to be pretty difficult after running suppressive compounds for 24 weeks straight. Your body needs a break. I’d PCT and then once your endocrine system is fully recovered decide if you want to start your next run.

  4. If I have good genetics for muscle building and I max out my nautral gains then I run LGD cycles on n off for couple of months.. what i wanted to ask is can someone look like connor murphy if they have capped natural potential + lgd only cycle? that is my goal body maybe not as much muscle mass but at least look that aesthetic shirtless


  5. Hi Derek,

    Can you guarantee that SARMS will have no effect on MPB, I am highly interested in Ostarine, I have never taken any steroid, nor prohormone since they speed up hairloss and I am already super prone to it, however thanks to you I started to use RU58841 and results are decent for now.

    So if I understood correctly from your article you suggest taking it for at least 12 weeks to notice effect when bulking and the dosage should be around 30 mg ?

    And the last question, I tried to search for high quality Ostarine on the internet only to find absolutely insane prices for so called pure Ostarine something around 200 bucks for 30ml/50mg, are you sure that the link you provided contains high quality Ostarine ?

    1. The sites I use that I linked in my articles are high quality as confirmed by HPLC testing, my own personal experience with them, and the thousands of other people who use them.

      SARMs should not accelerate MPB. At most, they might induce a temporary shed due to hormonal fluctuation, but I’m sure you already know that a shed isn’t permanent loss as it isn’t related to DHT wreaking havoc on the follice, as that is the only kind of loss that is permanent and related to androgenic alopecia. SARMs aren’t androgenic, and don’t convert to DHT, so they shouldn’t accelerate MPB at all.

      1. Hey derek, 2 questions
        If I take 5mg lgd 4033 and 20mg mk677 can I get away with just using nolvadex
        The other is if I want to prevent hair loss but am only going on just one cycle do I still have to use ru58841
        Science.bio is the only one that ships to turkey and they are currently out of stock
        Thank you

        1. 1) For PCT? Probably. Individual dependent though.
          2) You don’t have to do anything. RU will work while you are on it, and when you aren’t on it it won’t work. Not really much more to look into than that.

          1. It would literally be amazing if you could answer this man. I’m in a massive rush and am planning on purchasing mk677. As you know ru58841 isnt available to me at all so is there any possible chance that will affect my hair if I just do only one cycle for 12 weeks. Just only one cycle

            Lgd 5mg
            Mk677 20mg

            Pct most likely clomid

  6. Hi Derek,

    I know SARMs are not liver toxic but would is liver protection necessary if running osta+carda x 10 weeks + 4 week pct?


      1. Derek, thank you for what you provide. Can you recommend an example bulking diet plan while on sarms? I understand surplus, but would like an example of a days eating. I’m 5′ 11″ 190 skinny fat

  7. Hi Derek,

    My question it’s a bit different.
    I run rad140 for 10 weeks + EPI from week 4 to week 10. I want to do PCT after that, but can i do another 4 weeks just as ‘hardener’ – s4 (50mg) + gw (20mg) + osta (30mg) and then PCT ?

    Thanks for answer.
    Best regadrs,

    1. You can do whatever you want, you will just be more suppressed by the time you get to PCT. Not necessarily the worst thing in the world, but you’re prolonging the period of time you may or may not experience side effects of low test.

      1. Thank’s for really quick answer. Ok then, i think will be better to do 4 week PCT and then run new cycle with S4 + GW + Osta.
        In Your opinion, You will be add MK677 to PCT to help recovery etc. ?

        Thank’s Derek.

        1. Again, totally up to you. Yes it will help retain muscle during PCT, but it will also make you hungry and possibly overeat though, so if you are coming off of a cut then that could cause you to overeat during PCT and balloon up a bit.

          1. So better solution will be add GW to PCT cose that help muscle waste, right?
            To my blood work – my test isn’t suppressed much so i think 4 weeks PCT it’s enough. With MK677 You have right. I tried with Ostarine and i hold some water even when my diet was exactly the same all the time – clean.

            Thank’s again pall. Big help from You.
            Waiting for more vids.

  8. Hey bud,

    I just ordered Ostarine from the website you recommend. I know you mentioned that its safe if I have Arim-rx on hand incase of high estrogen. Is there anything else I need for the Ostarine Cycle?
    This will be my first Sarms cycle. BTW, thanks for the discount code.

      1. Hi Derek,
        I wanted to run my 1st cycle ostarine. So is this correct.
        8 weeks – 25mg per day
        PCT – 4 weeks Arimistane?
        I am confused about PCT, Some are saying Clomid, GW, or HC Generate ES or Arimistane.
        Please help.

  9. Hey Bud, I wants to run my first cycle of SARMS. My main goal is to bulk. But I dont know where to start from. Can you please help me to find right Product for first use. I was thinking about MK 677..

  10. Would you recommend a PCT fro a 4 week cycle of LDG 4033? and if so what PCT and mg intake weekly and daily would be recommended if any?

  11. What’s up Derek, first off, great website man, super cool. So, just last week I went and got my bloodwork done and am going to get the results back pretty soon, and I am on day 4 of my LGD 4033 cycle. I plan to take it for 60 days since I have the 60 capsule 5MG bottle from enhancedathlete and to just do 5 mg every day. I have been taking it in the morning every day. I plan to do Monday back and biceps Tuesday chest and triceps Wednesday legs and abs then Thursday shoulders traps and delts. Most of the time I go to the gym 5-6 times a week though, and I plan to build lean muscle with a lean muscle diet and heavy exercise. I know to take it every day regardless but at the most how many days should I have off from the gym? Thanks for the advice man.

    1. Depends on how much work load your body can handle relative to your nutrition. The answer is different for everyone, I can’t predict how much will be overkill for your body or not. I think working out 5 days a week with 2 rest days is pretty standard.

  12. How much lgd 4033 do i need to buy for a cycle to gain mass?
    if i did a cycle of 6-12 weeks and which post cycle would i need to use?

    1. Go read my LGD article and then do the math based on your dose. Read my PCT article. I have covered all these topics in depth. Use the search bar.

      1. I see that you are very active on responding so hopefully I can get a reply. I have never taken anything higher than protein and am finally at where I think my body has peaked. I have done research and have come to the conclusion that I want to run a cycle of Andarine. How much do I need to buy for a complete cycle? And are there any specific things I need to take with it or PC? Thanks in advance and sorry if it is a reiterated question. Just needing a straight answer form an experienced person.

        1. Depends how long you want to run it and at what dose. Just need to do the math bro. Yes you need to take PCT after. I have a separate article on that.

  13. I’m starting an eight week cycle of LGD and Cardarine in about a week. Would you suggest doing a PCT and then starting the next cycle again immediately, or waiting a while to start another cycle?

    1. That’s for you to decide, not me. If you’re recovered and your health markers are in check then when you do or don’t start is entirely up to you.

  14. I am starting a 12 week cycle of 10mg LGD(morning) and 20mg of MK67 (night), 1 arim per day, with a 4 week pct of Nolva/Clomid after (following your above dosage). Should I increase the amount of LGD during the cycle or will 10mg be sufficient? Also silly questions but if I am using liquid Nolva and Clomid, is it most effective to use a ml syringe to get the correct mg dosage amount? Will one bottle of each cover the 4 week pct?

    As always thanks for all the great info,


    1. What dose you use is entirely up to you, the sweet spot of LGD-4033 is typically 10mg though.

      For measuring it yes that would be the easiest way to measure it I imagine.

      You’d have to do the math to figure that out, I don’t know off the top of my head.

      1. 10 Mg/ML. For starters?? Quite a lot of money for a 30ml $90.00 dollar bottle. Lol I was under the assumption 1 mg a day for 30 days was sufficient? Ugh. Back to cheap old reliable creatine.

  15. Hey man,

    Gonna be running my first SARM cycle after training/dieting naturally for around 5 to 6 Years. I’ve picked up LGD and Ostarine as well as Nolva for PCT. What’s your best recommendation on how to stack them/doses/how long or also if I should just run one alone first to see how it goes.

    1. This article you just commented on explains why I don’t advise using 2 SARMs in a first cycle, nor would Nolva only be a PCT I recommend.

  16. I have a question. I’m considering starting an S4 cycle. I’ve been told I do not need a PCT as I am female… Thoughts? Thanks.

  17. Hey Derek. I’m going to run a 10 week cycle with Ostarine 20mg every day and cardarine (GW) 20 mg every day. If I’m planning to lose lots of fat while still retaining my muscle, how many calories should I eat below maintenance? I know Ostarine is incredibly muscle-sparing, so I just want to lose as much fat as I can. I’m 5’11 207 lbs, around 22% body fat.

      1. Yes I know that usually you would run a slight caloric deficit to lose weight naturally, but with SARMs, (Ostarine in particular) you can run at an even larger caloric deficit and lose fat faster while still retaining muscle and strength. Any idea how much more you could cut calories than normally on SARMs?

        1. That’s impossible to predict. I approach every cut the same regardless of what I am or am not using, and I suggest you do the same. Aggressive cutting should only be done if you have an impending deadline that is closer than ideal in my opinion. If you use a larger deficit, you will lose more fat initially, but you will also burn out quicker and plateau faster. Get the most fat loss out of each increment otherwise you are plateauing before necessary (aka you would’ve burned more overall fat if you were more patient without having to kill yourself with much lower calories than otherwise would’ve been necessary).

          1. Hey derek big supporter here
            Will I need to use ru58841 if I’m only going to do one cycle. If this is my first ans last do I still need to use it?
            Mk677 20mg
            Lgd 5mg

      2. FEBRUARY 26, 2020 AT 3:23 PM

        Hey derek big supporter here since 2016
        Will I need to use ru58841 if I’m only going to do one cycle. If this is my first and last do I still need to use it?
        Mk677 20mg
        Lgd 5mg

          1. I know I just didnt get it. Do you recommend I use it on only one cycle or it shouldn’t matter? Biggest fan here

  18. I was wondering if running a 12 week cycle of LGD 4033 with YK-11 would be an ok stack. I’m trying to get a decent bulking stack together but everything I read online suggests mixing all these different SARMS. I finally make up my mind just to change it because I read something different that somebody else suggested. Do you have any recommendations?

  19. I’m looking to do my first cycle of Ostarine and was looking into PCT I see enhanced athlete is out of stock on arimistane. Are there any other alternatives you would recommend?

  20. Hi Derek, I finished a 12 week cycle of Rad-140 End of January 2018….right now I’m doing a 4 week PCT with Clomid and D-Aspartic Acid into my 2nd week. I want to finish the rest of Feb with my pct. Will It be ok to run Ostamuscle right after my pct and start it beginning of March 2018 or would you suggest, waiting another 2 weeks after PCT and start Mk2866 Mid March?

  21. Hi, big fan of your vids and very helpfull information. Just started a cycle with
    mk677 20mg, rad140 10mg, androsta-3,5-dieen-7,17-dione 12.5mg
    Not looking to explode my body but am seeing significant difference allready. But can these low doses have indesired effects? Should I double my rad140 dose? Thanks!

    1. 1. Any drug can have side effects at any dose. They are just far less likely to occur at lower dosages.
      2. That’s your decision to make not mine.

      1. I just finished a 12 week cycle of S4, Osta and Cardarine. I used it for cutting, and got to around 9-10% bodyfat, I wanted to get 5-7% but it wasn’t enough time. Would it be foolish to continue my cut during my PCT (Nolva, Clomid) or do just add more calories and stick around maintenance until PCT is finished?

  22. Hey! So I want to start my first cycle. I want to gain lean muscle but try to stay lean. What SARN would you recommend? Also whatever you choose, what would you recommend to take either while or after cycle to prevent suppression and help keep muscle gains?

  23. Hey man,

    Going to try your beginners stack from your video. (Lbs 10mg, Mk 20mg) i understand about 75mg of arimistane per day would be sufficient for a pct after the cycle, but you mention taking one pill during as well. Is that roughly 25mg?

    1. One pill of Arim-RX (EnhancedAthlete Arimistane product name) is 25mg yes. Double check the label of whichever product you’re using though if you are using another brand.

  24. On Lgd 5 weeks……non stop eating
    But scale ain’t moving on weight gain
    But I’m looking bigger in mirror

  25. Hi Derek,
    I have been working out from 3-4 years naturally using protiens as supplements. I am planning to use SARMs for the first time. Maybe RAD140 or LGD for 10-12 weeks. As recommended by you i will use 1 SARM. Which one you recommend between both mentioned abouve or any other for lean muscle gain between both and dosage too?
    PCT will be nolvadex and clomid 4 weeks.

  26. hi thanks for this info ,
    I’m currently running austarine and lgd tablets, it says 4 weeks on 8 weeks off , would this mean 8 weeks after running a pct before jumping back on cycle, thanks in advance

    1. I don’t know what “it” is that’s saying that, but 4 weeks on is barely enough time to accomplish anything, and I don’t know what 8 weeks off means because I’m not the one who said that, but I’m guessing it means 8 weeks after PCT.

  27. Hey man just curious I have a question. I’m on 30 mg of ostarine and 12mg of lgd. Would a small dose of 4-andro be beneficial to my suppression? I’m talk like 100mg. Not looking for much, just enough to put some test in my body. Or would I be shooting myself in the foot? Thanks!

    1. I have no experience with 4-andro but I suppose if it converts to Testosterone in the body then it could be a good idea to mitigate any suppression symptoms.

      Typically I wouldn’t be adding anything in that would take you over the edge from moderately suppressed to completely shut down unless you were taking a SARM that was 100% going to shut you down anyways (like S23), or you started experiencing major low-test related side effects. That combo may be suppressive enough to justify it though.

  28. Hi Derek, thanks for the article.

    Just started my first cycle, with Ostarine. Currently in week 3 @ 12.5mg. I might up the dosage to 15 or 20mg depending on how I feel.

    Do you recommend a Arimistane or Clomid/Nova PCT for a 8 week cycle at 12.5 – 20mg?

    Also I got my pre cycle bloods done. When would be the correct time to get post cycle blood work done to see if my levels have return to normal and get accurate results?


    1. Depends on your pre-cycle bloods, your propensity to suppression, and your age, as well as what you’re willing to take. What were your test levels pre-cycle and how old are you?

  29. Hey man I’m about to start an 8 week cycle on ostarine..goals are gain a little, get more defined..pretty much recomp.. would you recommend a 12.5mg a day or 25mg a day for 8 weeks? Also would I need a pct for only 8 week course?

    1. I’d do 25.

      PCT is an absolute necessity in my opinion. If you are using something that will suppress your endocrine system I would advise PCT in some capacity.

      1. Sweet man..also I’m thinking about stacking mk677 with it for the last 4 weeks simply because I don’t have enough cash to get more haha ..would that be effective at all?? Or a waste of money? Thanks bro

  30. Alexandre Lemieux

    Hey there thanks a lot for your time im running a cycle of yk11+mk677+rad140 for about two weeks now i already gained 10pounds and got leaner i was taking .5ml of each everyday at night now i started taking .25ml when i wake up and .25 when i go to sleep i use sarmcenter gear i never took any anabolics before but i workout for more than two years now im 6′ 185pnds looking to be 200 shredded my diet is good i train the more i can twice a day when i can im looking for any input that could improve my gains if you can help me that would be greatly appreciated thanks for your help

      1. Alexandre Lemieux

        I understand that i should have gone through more research before taking these compounds but my body is reacting well to it up til now lets wish it stays that way i will probably experience a little suppression from what ive read on your posts so i will buy a pct soon and started taking the dosage according to your articles the only one i have to figure out is yk11 to see what works best for me thanks a lot for all the info

  31. Hi I’m about to run an 8week cycle of ostarine at 25mg + mk677 + tb500 (hoping to heal some of chronic back problems with this).

    I’ll be using arismistane at 25mg a day and then 75 mg for PCT after.

    Would you advise I add anything else in?


      1. Hey Derek, thanks for the reply, just wanted to say I’m a fan of your page and really appreciate all the information you’re getting out there.

        On that note, I’ve been on mk677 (30mg) + huoerzine A + ostarine (30mg) before bed for the past 5 days and have not felt anything (both from EA). Also added 20mg of cadarine from purerawz into the mix preworkout and still nada. I’ve seen most people say they feel the immediate effects which makes me question if I got a bad batch or something.

        When should I be expecting these compounds to kick in or is there a more effective way to take them?

  32. Hey I’m about to start a 12 week cycle of both Rad140 at 20mgs/day and Ostarine at 20mgs/day, is taking Arim-RX 25mgs/day on cycle and 75mg/day for 4 weeks post cycle a good idea and enough of a PCT?

    1. I’d use Clomid, or Nolvadex + Clomid for that personally (multiple compound cycles I would say always justify a “real” PCT).

  33. Hey,
    In some of your articles, you mention dosing in the morning. I have a rather spread out schedule with work, meaning that some days I’ll work late and sleep at 4am, wake up at around midday. Other days I start work at 8am, and not return home till about 4pm and hence go to bed around midnight.

    The only time that I am consistently at home is roughly 7-8pm, and that is when I dose my SARMS, to keep it consistent. Does it matter when you take it i.e. taking after waking up is better than before bed, or during the middle of the day?
    My suspicion is that it doesn’t matter unless you are taking MK-677 or SR, but clarification would be helpful.


    1. As long as you are taking the half life of whatever you are taking into consideration and dosing it to maintain stable blood serum concentrations it will be fine regardless if it’s morning or night. E.G. if you took LGD-4033 at night vs in the morning each day, it has a 24 half life so it wouldn’t make a difference. The only time dosing at different times of day would be an issue is if you weren’t being consistent each day and you were letting the compound work its’ way out of your system.

  34. Hi I’ll be running 25mg of Ostarine and 20mg of Cardarine on my first cycle ever. I have with me a Finaflex Revolution PCT, which has 50mg Aristamine per pill but with other supplements useful for PCT.

    I understand having an AI is important so you can take it the moment you feel any gyno or basically excess estrogen effects. Am I supposed to only take Aristamine to combat that during cycle or can I take the PCT pills during cycle?

    Thank you so much for your help.

    1. The only ingredient you need from that product is likely the Arimistane. I’m sure it could be used on cycle as your AI as well as during PCT. I don’t know the ingredients though.

  35. Do you recommend getting Testosterone levels checked before or after the SARM cycle? Is that something you’ve ever done?

  36. Hi guys I have been taking Ostarine & cardanine (20 mg) total for last 12 weeks but have noticed my cyling performance has gone backwards it may be a side effect of the 4 pounds of muscleI have gained, but my legs feel like they have no power?? Can anybody help with this ? I have decided to stop taking them as this can be the only reason. Will I feel even weaker after stopping i.e. testosterone low?

  37. Paul Bickerton

    Hi mate is it nessisary to run a cycle support compound when using a sarm? Such as cycle shield? Also I’m assuming DAA and Creatine are still ok on cycle? Thanks

  38. Will taking mk677, Ostarine and lgd-4033 at exactly the same time make any difference to effectiveness? Or should I split them up during the day..

  39. I just have a quick question for you man, first time anabolic user and i was planning on running Ostarine for 12 weeks then doing PCT. now i have seen a few places including your article to switch up compounds midway through the cycle. I have understood that first timers should run just Ostarine to introduce the compounds to your system. Would i be okay with running it for the full cycle, or should i switch up to rad-140 6 weeks in? Thank you.

  40. I purchased a 60mL from PP

    I want to take 10mg a day of LGD. Should I take 1mL, .5mL as marked on the dropper that comes with the bottle?

  41. Quick question, should I stack lgd with S4 for lean mass gain and shred at the same time or do lgd first then S4 separately ?

    1. You can’t gain lean mass and get shredded at the same time. Those are 2 counter productive goals to one another. Stacking vs not stacking would be dependent on experience and how far a physique has progressed.

  42. Question, I’m currrently running a cycle of Ostarine and Cardarine for 8 weeks (was planning to come extend it), although the website I bought this from has suspended all sales “due to the upcoming SARMs legislation”. Will there be a problem if I buy the same chemicals from a different website?

    1. I don’t have a guide. I imagine it’s as simple as mixing it fully in a vehicle like PEG 400 and measuring it out correctly. You’d have to find a definitive guide elsewhere, I’ve never done it.

  43. Hey Dereki am brand new to this SARMs thing and your articles have been helping me out a lot, but one thing I can’t seem to figure out is the dropper in the bottle is marked for ml and I can’t find out how many mg is in a ml. I know that’s a pretty stupid question I should just look it up but I have and found many different answers surprisingly lol

  44. Hi Derek,

    My question is if I can stack rad 140 with lgd 4033 for my first cycle for 8 weeks. Also should I take an AI with them and what pct do you recommend . Thank you in advance.

  45. Hey man I am currently running an 8 week cycle of lgd but plan on running a cycle of RAD 140 after. Do I need to run a full pct after my lgd cycle or can I go straight into a RAD 140 cycle?

  46. Hey there, great article man. I’m running into a small problem and hope you can help.
    It seems that some websites will say to run Mk-2866 during PCT with an AI. so just to be clear, I just did an 8 week cycle of LGD 4033 and GW. should I run the Mk2866 and then run my PCT after that?
    Thank you so much in advance.

  47. Esdras Heringer

    Hey Derek, really appreciate your work. I saw that you posted the websites to buy SARMS, however, where does one buy PCT products such as Clomid?

    Thank you!

    1. Those aren’t legal to sell. You would have to find those via a UGL, research chem site, or via a legitimate pharmacy.

  48. Hi Derek, I’m 30 years old, 5’8, 148lbs. I’ve been working out since I was 12 and although my weight is low I do have a decent build. I recently purchased a bottle of LGD-4033 (90 capsules – 5mg) and RAD-140 (90 capsules – 10mg). I want to bulk and build muscle, and in the end be more ripped than bulky. My instinct tells me to take LDG-4033 on it’s own to initially gain the bulk size and then cycle RAW-140 on it’s own afterwards to harden and get ripped. What is your recommended way for me to cycle or stack these two SARMS? Because my weight is so low would the minimum 5mg of LGD-4033 or 10mg of RAD-140 be enough to get good results? Should I do 4 weeks of LGD followed by 4 weeks of RAD or would it be better to stack them for 8 weeks. I can’t find any info on running them separate one after another, so any advice would be much appreciated. Thank you so much!

    1. You’re overthinking it. You getting ripped would be dependent on your diet. SARMs all activate the androgen receptor and will retain muscle in a deficit. You getting lean has nothing to do with which you choose.

      1. Thank you for the response. After re-reading this page I realized that you already stated not to take multiple SARMS at once for first time users. For as short as a typical cycle is, I guess with LGD or RAD either could potentially help me get to where I want to be if my diet and workouts are right. Since LGD is more known for bulking I think I am going to start with a 8 week cycle of 5mg. After a mini-pct and break, I will try a second cycle using 10mg of RAD and compare how the two effected me individually. Thank you!

  49. im 37, 6 feet tall, weigh in at a bout 235lbs. been hitting heavy weights for a while and got some good gains thus far. about a year ago i was 300lbs of mostly fat and wearing xxxL shirts. now im fitting into an XL and getting stronger. ive hit a plateau at this point. (just some background in case it helps)
    just got myself cardarine, ostarine, mk677, and andarine. plan on running 8 week long cycle. looking to do a recomp cycle to get harder and drop the overlying fat. got my pct ready with a natural test booster, aromitase inhibitor, and a cycle assist supplement for on cycle.
    i got no experience with sarms or gear.
    how am i looking with this stuff? right track? overkill?

  50. I stopped training since a month ago because I wasn’t making any progress and worse getting more injured. This is what typically happens to me for the last 7 yrs I have been lifting weights. I want to go back to strength training again but this time with Ostarine cycle. Do I have to start taking them from Day 1 or can I wait for 4-5 weeks to hit the plateau and introduce them when I cannot make progress further?
    I prefer latter but I would like to hear opinions, thanks!

  51. Hi, been lifting for about 6 months and would like to add a Sarm. Thinking about using Ostarine 15mg. capsules. Advice? Thanks.

    1. Just want to make sure I pick the right one to start with. I’m 62, 6’5″ 185. The classic ectomorph. I want to get the most out of it.

  52. Hi Derek,

    I’m 62 y.o. and am looking to start my first SARM cycle. I purchased Ostarine to start as it’s the mildest one. I am 6’5″ and 185 and very healthy. I’ve been very lean most of my life and looking to put on 5-10 lbs. of lean muscle. Any suggestions that will help me get the most out of this cycle? Dosage, workout? Thanks.

    1. I wouldn’t use anything suppressive at your age without first looking at HRT. Suppressing an already downregulated endocrine system is typically not going to end well.

    1. Ya, doctors say a lot of things. Look at your own blood work and make an informed decision. A doctor will tell you you’re fine with a 275 ng/dL total T.

  53. Hey Derek,

    My question is if I am currently on TRT and would like to take Ostarine for my first cycle of 8 to 12 weeks. Would I still need a pct. I would then like to try rad 140. What would your protocol be again for someone on TRT. I know rad 140 is supposed to be like testosterone but don’t know if they can be run together?

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